Melzer's solution: chemical reagent used on spores to determine if tissue or spores turn blue (amyloid), red/brown (dextrinoid), or no reaction (inamyloid). Formulation is: to Chloral Hydrate solution [dissolve 100 gm (ml) Chloral Hydrate in 100 ml water H2O] add 1.5 gm Iodine, 5.0 gm Potassium Iodide, dissolve.